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Table 4 Multivariable logistic regression on the association between having memory-related SCS and covariates (n=6,960)1;2

From: Memory-related subjective cognitive symptoms in the adult population: prevalence and associated factors – results of the LIFE-Adult-Study

Covariates3

df

Wald’s χ²

p value

OR

95%-CI

Sex, women vs. men

1

2.686

0.101

0.92

0.83-1.03

Age, every additional year

1

0.705

0.401

1.00

0.99-1.00

Education, with university degree vs. without

1

1.901

0.168

1.10

0.96-1.26

SES

 Medium vs. low

1

0.115

0.735

1.02

0.90-1.17

 High vs. los

1

2.727

0.099

0.84

0.69-1.03

Physical comorbidity, yes vs. no

 Arterial hypertension

1

0.163

0.687

0.98

0.88-1.09

 Hyperlipidemia

1

0.443

0.506

0.96

0.87-1.07

 Thyroid disease

1

2.960

0.085

1.10

0.99-1.24

 Cardiac arrhythmia

1

1.044

0.307

1.09

0.93-1.28

 Diabetes mellitus

1

0.165

0.684

1.04

0.88-1.23

 Any cancer

1

0.576

0.448

0.94

0.80-1.11

 Coronary heart disease/angina pectoris

1

0.017

0.897

1.02

0.75-1.40

 Myocardial infarction

1

1.723

0.189

1.28

0.89-1.84

 Stroke

1

0.001

0.972

1.01

0.70-1.44

 Cardiac insufficiency

1

0.032

0.857

0.97

0.68-1.38

 Epilepsy

1

1.620

0.203

0.77

0.51-1.15

 Peripheral artery occlusive disease/intermittent claudication

1

0.495

0.482

0.84

0.51-1.37

 Parkinson’s disease

1

0.312

0.576

0.76

0.29-1.98

 Multiple sclerosis

1

0.311

0.577

0.79

0.35-1.81

Depressive symptomatology

 CES-D score, every additional point

1

0.054

0.816

1.00

0.99-1.01

Anxiety

 GAD-7 score, every additional point

1

0.446

0.504

1.01

0.99-1.03

Cognition3

 VFT, every additional stated animal

1

0.026

9.871

1.00

0.99.1.01

  1. 1missing data for n = 1,874 (21.2%) of the 8,834 participants; 2Nagelkerke’s R² of the model = 0.004; 3The cognitive test results of Trail Making Test (TMT) A, TMT B and TMT ratio score B/A could not be additionally included into this regression model (model I) because the cognitive test results were not independent from each other. As a result, three additional regressions models (II-IV) were calculated including TMT A result (model II), TMT B result (model III), and TMT ratio score B/A result (model IV) instead of VFT test result as cognitive covariate. In these models, the different TMT tests results were also not significantly associated with having memory-related SCS: Every additional second in TMT A yielded an OR = 1.00 (95%-CI = 0.99-1.00; Wald’s χ² = 0.486, df=1, p=0.486; model II), every additional second in TMT B yielded an OR = 1.00 (95%-CI = 1.00-1.00; Wald’s χ² = 0.100, df=1, p=0.752; model III), and higher TMT ratio score B/A an OR =1.00 (95%-CI = 0.95-1.05; Wald’s χ² = 0.010, df=1, p=0.922; model IV). The replacement of the VFT test score by the other cognitive test results in regression model II-IV did not change the (non-significant) association of the other covariates with having memory-related SCS
  2. CES-D Center of Epidemiologic Studies Depression Scale, CI confidence interval, GAD-7 Generalized Anxiety Disorder Screener, df degree of freedom, OR odds ratio, SES socio-economic status, SCS subjective cognitive symptoms VFT Verbal Fluency Test
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BMC Psychology

ISSN: 2050-7283

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